Can you take fluconazole and metronidazole at same time?

NY

A 25-year-old female asked:

Is it okay to take metronidazole and diflucan (fluconazole) at the same time because i have bacterial vaginosis and a vaginal yeast infection?

3 doctor answers6 doctors weighed in

Can you take fluconazole and metronidazole at same time?

Pediatrics 59 years experience

Vaginosis: Yes you can take both medications together

3.8k viewsAnswered >2 years ago

Can you take fluconazole and metronidazole at same time?

General Surgery 32 years experience

Yes: It is OK to take both.

3.8k viewsReviewed >2 years ago

Can you take fluconazole and metronidazole at same time?

Podiatry 29 years experience

3.8k viewsReviewed >2 years ago

Last updated Feb 1, 2021

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Review

. 2019 Aug;71(4):321-328.

doi: 10.23736/S0026-4784.19.04388-0. Epub 2019 May 15.

Affiliations

  • PMID: 31106557
  • DOI: 10.23736/S0026-4784.19.04388-0

Review

Combined systemic (fluconazole) and topical (metronidazole + clotrimazole) therapy for a new approach to the treatment and prophylaxis of recurrent candidiasis

Carlo Genovese et al. Minerva Ginecol. 2019 Aug.

Abstract

Recurrent vulvovaginal candidiasis (RVVC) is an important pathological and infectious condition that can greatly impact a woman's health and quality of life. Clinical and epidemiological studies show that different types of therapies are able to eliminate the signs and symptoms of mycotic vaginitis in the acute phase, but so far none of these has proved able to significantly reduce the risk of long-term recurrence. In this review, based on the available literature and original data from a preliminary in-vitro microbiological study on the compatibility between fluconazole, clotrimazole and metronidazole a new therapeutic approach to RVVC is discussed and presented. The treatment proposed is a combined scheme using both systemic antimicrobial drug therapy with oral fluconazole 200 mg and topical drug therapy using the association metronidazole 500 mg and clotrimazole 100 mg (vaginal ovules) with adjuvant oral probiotic therapy. In detail, at the time of diagnosis in the acute symptom phase, we propose the following treatment scheme: fluconazole 200 mg on day 1, 4, 11, 26, then 1 dose/month for 3 months at the end of the menstrual cycle; plus metronidazole/clotrimazole ovules 1/day for 6 days the first week, then 1 ovule/day for 3 days the week before the menstrual cycle for 3 months; plus probiotic 1 dose/day for 10 days for 3 months starting from the second month to the end of the menstrual cycle. This scheme aims to address the recurrent infection aggressively from the outset by attempting not only to treat acute symptoms, but also to prevent a new event by countering many of the potential risk factors of recurrence, such as the intestinal Candida reservoir, the mycotic biorhythm, the formation of biofilm, the phenotype switching and the presence of infections complicated by the presence of C. non albicans or G. Vaginalis, without interfering, but rather favoring the restoration of the vaginal lactobacillus species. Future clinical studies will be useful to confirm the proposed scheme.

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Can antibiotics and fluconazole be taken together?

They may prescribe an oral antifungal pill called fluconazole (Diflucan) for you to take during your course of antibiotics. You might be instructed to take one pill on the first day and another pill every seven days until you finish the antibiotics.

Is fluconazole and metroNIDAZOLE the same?

Metronidazole vs. Fluconazole. Metronidazole and fluconazole are used to treat different types of vaginal infections. Metronidazole is an antibiotic used to treat bacterial vaginosis and trichomonas vaginal infections, and fluconazole is an antifungal used to treat vaginal fungal infections caused by Candida.

Can you take metroNIDAZOLE if you have a yeast infection?

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing the bacteria or preventing their growth. However, this medicine will not work for vaginal fungus or yeast infections. This medicine is available only with your doctor's prescription.

What drugs should not be taken with metroNIDAZOLE?

Taking or using metronidazole with other medicines and herbal supplements.
warfarin, a medicine that helps to treat and prevent blood clots..
lithium, used to treat some types of mental health conditions..
disulfiram, used to help people stay off alcohol..
phenytoin or phenobarbitone, used to treat epilepsy..