Alternately, an SN2 mechanism in which the formation of the amide oxygen-ribose carbon bond is concurrent with the displacement of the nicotinamide group and proceeds through a pentavalent transition state. From: Methods in Enzymology, 2016
Alternately, an SN2 mechanism in which the formation of the amide oxygen-ribose carbon bond is concurrent with the displacement of the nicotinamide group and proceeds through a pentavalent transition state. From: Methods in Enzymology, 2016