How often can you take NightTime cold and flu?

Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist have told you.

• Keep this leaflet. You may need to read it again.
• Ask your pharmacist if you need more information or advice.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
• You must talk to a doctor if you do not feel better or if you feel worse after 3 days.

1. What this medicine is and what it is used for
2. What you need to know before you take this medicine
3. How to take this medicine
4. Possible side effects
5. How to store this medicine
6. Contents of the pack and other information

• paracetamol which is a pain reliever (analgesic) and helps reduce your temperature when you have a fever
• phenylephrine which is a decongestant to reduce swelling in the passages of the nose to help you breathe more easily.

• caffeine which helps to increase the pain relief from paracetamol and makes you more alert.

These capsules are used for the relief of the symptoms of colds and flu, including aches and pains, sore throat, headache, nasal congestion (blocked nose) and feverishness (high temperature). The Day capsules can also relieve tiredness and drowsiness.

• are allergic to paracetamol, caffeine, phenylephrine or any of the other ingredients
• have a serious heart condition or cardiovascular disorder(s)
• have high blood pressure (hypertension)
• have a history of stomach ulcers
• have an overactive thyroid
• have an enlarged prostate
• are taking antidepressant drugs called monoamine oxidase inhibitors (MAOI’s), or have taken them within the last 14 days - these are medicines such as phenelzine and isocarboxazid.

Talk to your doctor or pharmacist before taking this medicine if you:

• are pregnant or breast-feeding
• suffer from kidney or liver problems, including alcoholic liver disease
• have diabetes
• have circulatory disorders such as a condition called Raynaud’s Phenomenon, which results from poor circulation in the fingers and toes.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines especially:

• medicines to treat high cholesterol levels which reduce the amount of fat in the blood such as colestyramine
• medicines to control feeling sick or being sick such as metoclopramide or domperidone
• medicines called anti-coagulants, which are used to thin the blood such as warfarin or other coumarins – you may take occasional doses of paracetamol but should consult your doctor if you need to take it on a regular basis
• barbiturates (for epilepsy or to help you sleep), such as phenobarbitones
• tricyclic antidepressants such as imipramine, amitriptyline
• medicines to lower blood pressure, treat heart or circulatory problems such as beta blockers (e.g. atenolol) or vasodilators (e.g. hydralazine)
• other decongestant drugs such as ephedrine or xylometazoline.

Do not take anything else containing paracetamol while taking this medicine.

Do not drink alcohol (beer, wine, spirits etc) while taking this product.

This medicine contains less than 1 mmol sodium (23 mg) per capsule, that is to say essentially ‘sodium-free’.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Swallow the capsules whole with water. Do not chew.

Take 2 Day capsules every 4 to 6 hours during the daytime, as required

and

Take 2 Night capsules at bedtime.

Leave at least 4 to 6 hours between doses.

Do not take more than 8 capsules (4 doses) in any 24 hour period.

Do not take more medicine than the label tells you to. If you do not get better, talk to your doctor.

Do not take for longer than 3 day, unless advised by your doctor.

The Day time capsules contain caffeine which may disrupt sleep if taken at night.

Talk to a doctor at once if you take too much of this medicine even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage. Go to your nearest hospital casualty department. Take your medicine and this leaflet with you.

Most people do not have any side effects while taking this medicine. However, if you experience any of the following side effects, or anything else unusual happens, stop taking the medicine immediately, and see your doctor or pharmacist.

• allergic reactions such as skin rash
• tingling and coolness of the skin
• a faster or slower heart beat
• a rise in blood pressure with headache, vomiting (being sick) and irregular heart beat (palpitations)
• nausea (feeling sick) (Day Capsule only)
• difficulty sleeping (insomnia) (Day Capsule only).

Very rare cases of serious skin reactions have been reported.

You may become more prone to bleeding, bruising, fever and infections, such as sore throat and ulcers, due to changes in your blood.

Problems or pain passing urine. This is more likely to occur in men with an enlarged prostate gland.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date printed on the pack.

Do not store above 25°C.

Day Capsules:

The active ingredients are paracetamol, phenylephrine hydrochloride and caffeine.

Each Day capsule contains paracetamol 500 mg, caffeine 25 mg and phenylephrine hydrochloride 6.1 mg.

The other ingredients in the Day capsules are: maize starch, croscarmellose sodium, sodium laurilsulfate, magnesium stearate and talc. The capsule shell is made of gelatin and contains the colours: quinoline yellow (E104), titanium dioxide (E171), patent blue V (E131) and erythrosine (E127).

Night Capsules:

The active ingredients are paracetamol and phenylephrine hydrochloride.

Each Night capsule contains paracetamol 500 mg and phenylephrine hydrochloride 6.1 mg.

The other ingredients in the Night capsules are: maize starch, croscarmellose sodium, sodium laurilsulfate, magnesium stearate and talc. The capsule shell is made of gelatin and contains the colours titanium dioxide (E171), erythrosine (E127) and indigo carmine (E132).

The pack contains 12 red and yellow coloured Day capsules and 4 dark blue and light blue coloured Night capsules.

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