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An action potential is a rapid rise and subsequent fall in voltage or membrane potential across a cellular membrane with a characteristic pattern. Sufficient current is required to initiate a voltage response in a cell membrane; if the current is insufficient to depolarize the membrane to the threshold level, an action potential will not fire. Examples of cells that signal via action potentials are neurons and muscle cells.
For more information, please register to download our Guide, the Axon Guide. << Back to Patch-Clamp Basics More great resourcesHow does resting membrane potential become action potential?During the resting state, the membrane potential arises because the membrane is predominantly permeable to K+. An action potential begins at the axon hillock as a result of depolarisation. During depolarisation voltage-gated sodium ion channels open due to an electrical stimulus.
What is resting membrane potential?The resting membrane potential of a neuron is the electrical potential inside the cell relative to the adjacent extracellular space.
What is the difference between and resting potential?Resting potential does not allow the transmission of nerve impulses at rest, while action potential allows the transmission of nerve impulses through the membrane.
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